Health Effects Support Document for Naphthalene.
The U.S. Environmental Protection Agency (EPA) has prepared this Drinking Water Support Document to assist in determining whether to establish a National Primary Drinking Water Regulation (NPDWR) for napthalene. Case study reports from humans ahd laboratory studies with animals demonstrate that napthalene can have adverse effects on the oxidation state of hemoglobin (Methemoglobinemia), the structural integrity of the red blood cell membrane (hemolysis), the activity of selected hepatic enzymes, and body weight gain following oral exposure. It also contributes to the formation of cataracts in certain species and strains of laboratory animals. These effects tend to occur at moderate-to-high doses that are unlikely to be found in public water systems.
|Napthalene; Health effects; Drinking water; Risk assessment; Toxicity; Contaminants; Epidemiology; Case studies; Exposure; Bicyclic aromatic hydrocarbon|
|Office of Water|
|Health and Ecological Criteria Division|
|Office of Science and Technology|
|Donohue, Joyce Morrissey|